Emergency:

Helpline:

Skin Cancer Causes: Unravelling the Risk Factors & Prevention Tips

By Dr. Muzammil Shaikh in Nanavati Max Institute of Cancer Care

Aug 06 , 2024 | 7 min read

Skin cancer signifies an abnormal proliferation of skin cells, typically stimulated by excessive ultraviolet (UV) radiation exposure from the sun or tanning beds. It holds the dubious distinction of being the most prevalent form of cancer globally.

Melanoma is marked as the 17th most common cancer worldwide with over 325,000 new cases surfacing in 2020. In the United States, skin cancer outnumbers all other cancers with over 9,500 new diagnoses every day. More than 5.4 million cases of nonmelanoma skin cancer are treated each year.


Skin Cancer Causes

Skin cancer is primarily caused by excessive exposure to ultraviolet (UV) radiation from the sun or tanning beds, along with genetic and environmental factors. Excessive exposure to sunlight is one of the prominent skin cancer causes. It's crucial to understand the link between UV radiation and skin cancer to outline effective prevention strategies.

Sunlight and Skin Cancer

Sun exposure plays a significant role in the development of skin cancer. To understand this, let’s break it down:

  • UV Radiation: Prolonged exposure to the sun's ultraviolet (UV) radiation is one of the primary skin cancer causes. UV radiation can cause damage to the DNA in skin cells, which can lead to the development of cancer over time.
  • Types of UV Rays: There are two types of UV rays - UVA and UVB. Both forms can harm the skin and increase an individual's risk of skin cancer. UVA rays penetrate deep into the skin and are responsible for premature ageing while UVB rays are more likely to cause sunburn and play a key role in developing skin cancer.

Impact of Sunburn on Skin Cancer

Did you know that experiences of severe sunburn can escalate your risk for skin cancer?

  • Severe Sunburns: Overexposure to the sun, causing severe sunburns, may lead to skin cancer. The damaged skin cells can develop mutations, potentially resulting in cancerous growths.
  • Correlation with Skin Cancer: Research indicates a strong correlation between severe, repeated sunburns and increased risk of skin cancer.

A person can prevent sunburn by:

  • Using sunscreen regularly with good SPF protection
  • Seeking shade when the sun's rays are strongest (between 10 am – 4 pm)
  • Wearing protective gear like hats, sunglasses and long-sleeved clothing

Geographic Factors and Sun Exposure

Awareness about geographic factors can aid in devising focused prevention strategies and facilitating timely treatment for skin cancer where required. Where a person lives can significantly impact one's sun exposure level, determining the skin cancer risk. Why? The reason is that the closer that person is to the equator, the more direct sunlight he/she receives. An increased rate of skin cancer is noted in tropical regions like Kerala and coastal areas due to increased sun exposure. Residents of regions also face higher risk as sunlight is stronger at elevated altitudes.

This understanding of how sun exposure influences skin cancer development helps us take better protective measures, enhancing the effectiveness of any subsequent Skin Cancer Treatment.


Other Skin Cancer Causes

Understanding skin cancer involves more than just knowing about harmful UV radiation. It's also crucial to understand other factors that contribute to this condition. Let's delve into these causes.

Genetic Factors

  • Genetics can significantly impact the risk of developing skin cancer.
  • Familial patterns and genetic predispositions can increase susceptibility to the disease. For instance, having a family history of skin cancer puts a person at a higher risk.
  • Certain inherited conditions or mutations such as xeroderma pigmentosum can also heighten this risk.

Environmental Factors

  • The environment is filled with potential hazards for skin health, including pollutants and consuming water contaminated with substances like arsenic.
  • Such exposure can lead to an increased risk of skin cancer.
  • Some practical steps towards reducing this risk include consumption of safe drinking water and maintaining a clean environment.

Lifestyle Choices and Habits

  • Lifestyle is a significant determinant when it comes to skin cancer risk.
  • Habits like smoking, poor dietary choices and excessive alcohol consumption have been linked to an increased likelihood of developing skin cancer.
  • Adopting a skin-friendly lifestyle can help minimise this risk. This includes quitting smoking, maintaining a balanced diet rich in antioxidants, staying hydrated and protecting one's skin from environmental factors with sunscreen and protective clothing.


Skin Cancer Prevention and Protection

Shielding oneself from the sun's harmful ultraviolet (UV) rays is a task of utmost importance. Here are some effective sun protection measures that a person should adopt:

Sun Protection Measures

  • Use of Sunscreen: Slather a broad-spectrum sunscreen with an SPF of at least 30 on all exposed skin 15 minutes before stepping outdoors. Ensure to reapply every two hours, irrespective of the weather and after activities causing perspiration or involving water.
  • Wearing Protective Clothing: Opt for long-sleeved shirts, trousers, wide-brimmed hats and sunglasses that offer UV protection. Clothes boasting a UV protection factor (UPF) or crafted out of tightly woven fabric provide additional safety.
  • Seeking Shade: Find relief under the shade between 10 am and 4 pm, when the sun's UV rays are at their peak intensity.
  • Regular Skin Checks: Keep a close eye on changes in moles or skin lesions as early detection can be crucial in treating melanoma, one of the skin cancer causes.

Genetic Counselling and Screening

  • Genetic counselling is a significant step in managing the risk of skin cancer, especially for those with a family history of the disease. This assessment estimates an individual's risk based on personal and family medical history, nudges decisions on genetic testing, and imparts information on preventive measures. This procedure is vital for individuals with specific risk factors such as multiple family members with melanoma or early-onset melanoma.
    • Genetic testing aids in identifying inherited mutations linked to melanoma, aiding risk assessment and planning personalised treatment for skin cancer. This type of testing can ascertain if an individual carries gene mutations associated with melanoma like the CDKN2A gene or other genes such as BRCA2, PTEN, TP53, BAP1, and MITF.
  • With rapid advancements in understanding melanoma genetics, there are now more testing options available like panel tests that screen multiple genes at once.
  • Screening options are critical for individuals at higher genetic risk. Regular skin exams by doctors and self-exams are recommended. Screenings may differ based on individual risk factors identified through genetic counselling and testing.

Healthy Lifestyle Practices

A key aspect in preventing skin cancer lies in adopting certain practices that can help maintain a healthy lifestyle. These include:

  • Healthy Diet: Consuming a balanced diet comprising fruits, vegetables, whole grains and lean proteins is crucial. This not only supports overall health but also maintains skin health by providing necessary nutrients.
  • Regular Exercise: Engaging in physical activity for at least 150 minutes per week can boost the immune system and promote overall health.
  • Regular Skin Checks: Examine skin regularly for any changes in moles or spots. Also, schedule regular visits to the dermatologist for early detection of any potential issues.
  • Healthy Habits: Quit smoking and limit alcohol intake as both smoking and alcohol can increase the risk of skin cancer.

To recap, skin cancer causes include UV radiation exposure, genetic predisposition and environmental exposures. It is important to note that early detection through regular skin health monitoring can significantly improve skin cancer treatment outcomes.

Therefore, it is crucial to protect skin from UV light, regularly check skin for moles or changes and consult with a skin cancer doctor for annual skin exams.


Frequently Asked Questions

1. Why is understanding the causes of skin cancer important?

Understanding the causes of skin cancer helps in effective prevention and early detection, thereby improving treatment outcomes.

2. How does sun exposure contribute to skin cancer?

Overexposure to the sun's harmful ultraviolet rays can cause damage to the skin cells, leading to mutations that result in skin cancer.

3. Are there factors beyond sun exposure that contribute to skin cancer?

Yes, factors such as age, family history, fair complexion and exposure to certain chemicals or radiation can also contribute to skin cancer.

4. How can I protect myself from skin cancer?

Protect yourself by limiting sun exposure, using sunscreen periodically, wearing protective clothing and regularly checking your skin for signs of changes.

5. Is there a connection between genetics and skin cancer?

Yes, individuals with a family history of skin cancer are at a higher risk of developing the disease themselves.

6. Is skin cancer curable?

Most types of skin cancer are curable if detected and treated early.

7. What is the youngest age to get skin cancer?

Skin cancer primarily affects adults but it can occur at any age including childhood, though it's rare.

8. Where does skin cancer start?

Skin cancer often starts in areas most exposed to the sun like face, neck, hands but it can start anywhere on the body.

9. What is the best treatment for skin cancer?

Treatment for skin cancer varies based on its type, stage and location. Options include surgery, chemotherapy, immunotherapy, radiation therapy or systemic treatments.

10. What are the 7 warning symptoms of skin cancer?

The seven signs include changes in size, shape or colour of a mole; non-healing sores; redness or swelling; itchiness or pain around moles.

11. What blood tests detect skin cancer?

There isn’t a specific blood test for detecting skin cancer. Diagnosis typically involves visual examination and biopsy of suspicious skin lesions.

12. What type of skin cancer is the most curable?

Basal cell carcinoma, a type of skin cancer, is considered the most curable due to its slow growth and high response rate to treatment.